Predicting susceptibility for temporomandibular disorders – emerging possibilities from combining registries

Presentatörer:
Vallin S¹, Visscher CM², Lobbezoo F², Häggman-Henrikson B³, Bernt Lindahl⁴, Lövgren A¹

¹Department of Odontology, Umeå, Sweden
²Department of Orofacial Pain and Dysfunction, Amsterdam, the Netherlands
³Department of Orofacial Pain and Jaw Function, Malmö, Sweden
⁴Department of Public Health and Clinical Medicine, Umeå, Sweden

Background: Chronic pain from temporomandibular disorders (TMD), significantly impacts the lives of those affected. The multifactorial etiology and association with lifestyle factors necessitate further exploration to target interventions for effective management.

Aim: to determine the representativeness of a merged cohort for TMD and explore the ability to predict individual susceptibilities using available registries.

Methods: This study was conducted in Västerbotten during 2010-2017, using the community sample of a TMD register (n=203,208). Individuals with a positive response to at least one of the three screening questions (3Q/TMD) were classified as ’TMD cases’. The Västerbotten Intervention Programme (VIP) provided comprehensive socio-demographic, lifestyle, and health-related data (n ≈ 100,000).

Results: Merging the TMD and VIP data resulted in a cohort of 59,408 unique individuals. Of these, 51.1% were women with a mean age of 44.9 years. The prevalence of TMD was 8.5%. Women reported a higher prevalence of TMD (12.3%) than men (5.2%). Individuals with TMD reported more sick leave (X2 P<0.001) and rated their general health as worse (X2 P<0.001).

Conclusions: The merged cohort, consisting of TMD community samples and VIP participants, reflects the age and gender distribution of the general population, allowing extensive large-scale analysis.